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Zoekresultaten - 97 results

Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo.

Number 2336, p.2328- 2336 (2012) Keywords: access Activity Adult Agonist-selective coupling an analysi analysis AS brain cause CB1 cannabinoid receptor Control data Dopamine DRUG effect effects evidence ...

The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer

receptors CXCR1, CXCR2, CXCR3 and CXCR4) on the transition of chronic inflammation in the upper gastrointestinal tract to neoplasia. CXCR2 ligands, including GRO-α,β,γ/ CXCL1,2,3, ENA-78/ CXCL5 and IL-8/ ...

The expression and role of CXC chemokines in colorectal cancer

leukocytes to inflammatory sites. Nowadays, it is clear that CXC chemokines and their receptors (CXCR) may also modulate tumor behavior by several important mechanisms: regulation of angiogenesis, activation ...

Circulating bone-marrow-derived endothelial precursor cells contribute to neovascularization in diabetic epiretinal membranes

studied by immunohistochemistry using antibodies against CD133, vascular endothelial growth factor receptor-2 (VEGFR-2), CD14, SDF-1 and CXCR4. RESULTS: Blood vessels expressed CD133, VEGFR-2, CD14, SDF-1 ...

Capsid proteins from field strains of foot-and-mouth disease virus confer a pathogenic phenotype in cattle on an attenuated, cell-culture-adapted virus

characterization of receptor utilization in vivo. Health Topics:  Animal health Santé animale Diergezondheid Manuscript versions:  DOI:  http://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.029710-0 ...

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules36549

metabolism Monoclonal antibodies monoclonal-antibodies Multiple Netherlands ON Phage Display prevention protection protein Proteins Rabies Rabies virus RANGE Receptor Research Research Support Respiratory ...

Binding of “AT4 receptor” ligands to insulin regulated aminopeptidase (IRAP) in intact Chinese hamster ovary cells

Publication Type: Peer reviewed scientific article Authors: Heidi Demaegdt; Paul Gard; Jean-Paul De Backer; Aneta Lukaszuk; Erzsébet Szemenyei; Géza Tóth; Dirk é; Georges Vauquelin Source: Molecular and Cellular Endocrinology, Volume 339, Issue 1-2 (2011) ...

The bovine herpesvirus 4 Bo10 gene encodes a nonessential viral envelope protein that regulates viral tropism through both positive and negative effects.

attachment both by binding to cells and by covering another receptor-binding protein until they are displaced. Thus, they regulate viral tropism both positively and negatively depending upon the presence or ...

Effect of PstS sub-units or PknD deficiency on the survival of Mycobacterium tuberculosis.

another potential Pi receptor, PknD, we constructed and complemented their knockout (KO) mutants. In Sauton medium, the PstS1-3 KO grew faster than the Wt or the PknD KO. Following 24 h of complete ...

Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a 'two-step' competition binding approach.

Competitive Cho Cells Computer Simulation Cricetinae Cricetulus HEK293 Cells Humans Ligands Protein Binding Radioligand Assay Receptor, Cannabinoid, CB1 Receptors, Dopamine D2 Abstract: BACKGROUND AND PURPOSE: ...

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