Zoekresultaten - 15 results
Chemometrics and chromatographic fingerprints to classify plant food supplements according to the content of regulated plants.
regulated or toxic plants is an important issue, especially when the products are purchased from irregular sources. This paper focusses on this problem by using specific chromatographic fingerprints for five ...
Detection of regulated herbs and plants in plant food supplements and traditional medicines using infrared spectroscopy.
identification of a specific toxic or regulated plant in herbal preparations or plant food supplements is a real challenge, since they are often powdered, mixed with other herbal or synthetic powders and ...
The use of Stationary Phase Optimized Selectivity Liquid Chromatography for the development of herbal fingerprints to detect targeted plants in plant food supplements.
control is performed and that they could contain herbs or plants that are regulated. Stationary Phase Optimized Selectivity Liquid Chromatography (SOS- LC) was evaluated for the development of specific ...
Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).
for drug developers and regulators were presented. These methods are described in the present report: they include five advanced methods for data analysis (empirical regression models, pharmacometrics ...
Commentary on the MID3 Good Practices Paper.
regulators agreed to the necessity to build expertise to be able to review M&S data provided by companies in their dossier. This led to the establishment of the EMA Modelling and Simulation Working Group ...
Chromatographic fingerprinting as a strategy to identify regulated plants in illegal herbal supplements.
Publication Type: Peer reviewed scientific article Authors: Custers, D; Van Praag, N; Patricia Courselle; Apers, S; Eric Deconinck Source: Talanta, Volume 164, p.490-502 (2017) Abstract: Erectile dysfunction (ED) is a sexual disorder characterized by the ...
The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells.
investigated how HLA-G expression is linked to the patterns of promoter methylation and explored the role of the 3’ UTR polymorphic sites and their binding microRNAs on the post-transcriptional regulation of ...
An application of mass spectrometry for quality control of biologicals: Highly sensitive profiling of plasma residuals in human plasma-derived immunoglobulin.
residual proteins between Ig products. A TEE-positive batch was distinguished by unique profile of residual proteins, including FXI a but also various blood stream-regulator proteins (fibrinogen, ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
Issue 9, p.2215-29 (2016) Keywords: Carcinogens Cell Line, Tumor Computational Biology Dose-Response Relationship, Drug Gene Expression Profiling Gene Expression Regulation Genome-Wide Association Study ...
In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics.
information. In the EU, dermal absorption has to be assessed in vitro since the Cosmetic Regulation 1223/2009/ EC forbids the use of animals. To obtain human-relevant data, a Franz diffusion cell protocol was ...