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Zoekresultaten - 215 results
Identifying essential COVID-19 indicators for primary healthcare through Delphi analysis in 31 European countries: Eurodata eDelphi study
current pandemic, with participants rating the relevance and utility of proposed indicators. Results: Of the 22 initial indicators, seven received consensuses for inclusion, while two remained contentious ...
Host transcriptome profiling for resistance against lumpy skin disease (LSD).
post-infection may be a critical time point for LSD infection. The Gene Ontology (GO) and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway enrichment test showed a few enriched GO terms and pathways relevant ...
Advancing regulatory dialogue: In silico models for improved vaccine biomanufacturing- an expert meeting report.
relevant to vaccine biomanufacturing and shelf life. The stability model was highlighted as having the most significant impact on the common technical document (CTD) due to its potential to streamline data ...
Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
identified following screening against the most relevant trypanosome species. Selected hit compounds were extensively tested for metabolic stability, potency in mouse models for the various species, ...
Galaxy @Sciensano: a comprehensive bioinformatics portal for genomics-based microbial typing, characterization, and outbreak detection.
reports with key findings. These pipelines include quality control, de novo assembly, sequence typing, antimicrobial resistance prediction and several relevant species-specific assays. They are tailored for ...
VERMEER FCM: A tool integrating exposure and hazard modelling for chemicals migrating from food contact materials.
with Regulation (EU) No 10/2011 for plastic FCM. Overall, the tool consists of three modules that allow (i) to model the migration of chemicals into food, (ii) to predict toxicological endpoints relevant ...
Phage-Mediated Digestive Decolonization in a Gut-On-A-Chip Model: A Tale of Gut-Specific Bacterial Prosperity.
These were used to better understand bacterial dynamics under phage pressure using two relevant species: and. Model mucus secretion was documented by ELISA assays. Bacterial dynamics assays were performed ...
Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals.
reliance on experimental animals, new approach methodologies (NAM s) that provide human-relevant dose-response data are needed. Two transcriptomic biomarkers, GENOMARK and TG x- DDI, have shown a high ...
Maintaining the quality of vaccines through the use of standards: Current challenges and future opportunities.
ever-increasing complexity, diversity, and number of vaccine products as well as increasing efforts to replace animal-based potency tests with in vitro assays that measure relevant quality attributes. As such, ...
A survey of the representativeness and usefulness of wastewater-based surveillance systems in 10 countries across Europe in 2023
systems, and shared information about WBS of other pathogens as deemed relevant. SARS-CoV-2 WBS systems primarily monitored national and subnational trends (population coverage: 25–99%), and a majority ...