Zoekresultaten - 60 results
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
RdRp. Docking of LZ37 in the crystal structure of the BVDV RdRp revealed several potential contacts including: (i) hydrophobic contacts of LZ37 with A221, A222, G223, F224 and A392; (ii) a stacking ...
NUSAP method for evaluating the data quality in a quantitative microbial risk assessment model for Salmonella in the pork production chain.
in the QMRA model. The NUSAP methodology and kite diagrams are objective tools to discuss and visualize the quality of the parameters in a structured way. These two tools can be used in the selection ...
Electron tomography of negatively stained complex viruses: application in their diagnosis.
allows visualizing and measuring artifacts typical for negative staining. This approach allows sharp visualisation of structures in a subnanometer-thick plane, avoiding blurring due to superposition which ...
Type and frequency of contacts between Belgian pig herds.
herd type and other factors. Skewness of both direct and indirect contacts, illustrated that there was a wide variety in contact structure between pig herds in Belgium. Infection control might benefit by ...
The polymeric stability of the Escherichia coli F4 (K88) fimbriae enhances its mucosal immunogenicity following oral immunization.
fimbriae bind to the F4 receptor (F4R) in the intestine and induce a protective F4-specific immune response. F4 fimbriae are very stable polymeric structures composed of some minor subunits and a major ...
A Bayesian evaluation of six diagnostic tests for foot-and-mouth disease for vaccinated and non-vaccinated cattle.
disease (FMD) to discriminate between sero-converted (for non-structural FMD virus proteins) and non-sero-converted cattle were evaluated for vaccinated and unvaccinated cattle. Since none of the tests ...
FMD vaccines: reflections on quality aspects for applicability in European disease control policy.
are elaborated with emphasis on quality assurance/quality control (QA / QC). The purity of the vaccine in respect of the presence of non-structural protein antibodies could be checked indirectly by ...
Expression of reelin, its receptors and its intracellular signaling protein, Disabled1 in the canary brain: relationships with the song control system.
Reelin Protein Serine Endopeptidases Abstract: Songbirds produce learned vocalizations that are controlled by a specialized network of neural structures, the song control system. Several nuclei in this ...
Use of continuous results to compare ELISAs for the detection of antibodies to non-structural proteins of foot-and-mouth disease virus.
Sensitivity and Specificity Viral Nonstructural Proteins Abstract: Six tests for detection of antibodies against the non-structural proteins of foot-and-mouth disease virus (FMDV) were compared at an ...
Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.
Three-Dimensional Imidazoles Inhibitory Concentration 50 Models, Molecular Molecular Structure polymerase chain reaction Pyridines RNA Replicase RNA, Viral Sequence Analysis, DNA Structure-Activity Relationship Virus ...