CD57, a marker for B-cell activation and splenic ellipsoid-associated reticular cells of the chicken.

Last updated on 22-8-2019 by Anonymous (niet gecontroleerd)

Public Access


Peer reviewed scientific article



We have demonstrated that the ellipsoid-associated reticular cells of chicken spleen express CD57, a marker for B-cell activation. These cells are characterised by their spindle-shaped morphology, tissue distribution and the absence of certain leucocyte-specific markers. They are phagocytotic and possess high endogenous non-specific esterase activity. Previous reports failed to detect CD57 expression on ellipsoid-associated reticular cells, probably because the tissue sections were differently treated before immunohistochemistry. CD57 is also expressed by a small number of T-cells in the sp…

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