Detecting cervical precancer and reaching underscreened women by using HPV testing on self samples: updated meta-analyses.

Last updated on 7-6-2023 by Marie Malingreau

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OBJECTIVE: To evaluate the diagnostic accuracy of high-risk human papillomavirus (hrHPV) assays on self samples and the efficacy of self sampling strategies to reach underscreened women. DESIGN: Updated meta-analysis. DATA SOURCES: Medline (PubMed), Embase, and CENTRAL from 1 January 2013 to 15 April 2018 (accuracy review), and 1 January 2014 to 15 April 2018 (participation review). REVIEW METHODS: Accuracy review: hrHPV assay on a vaginal self sample and a clinician sample; and verification of the presence of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) by colposcop…

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