Food contamination with pyrrolizidine alkaloids: the expected… and the unexpected

Last updated on 22-8-2019 by Anonymous (niet gecontroleerd)

Scientific poster, presentation or proceeding





Pyrrolizidine alkaloids (PAs) and their N-oxides (PANOs) are natural toxins, exclusively biosynthesized by a wide variety of plant species (>6000). They are secondary plant metabolites against herbivores and are believed to be one of the most widely spread natural toxins. PAs and PANOs can become a significant public human health problem from the intake of contaminated food of botanical or animal origin. Human poisoning cases have been documented, are mainly characterized by acute and chronic liver damage, and can lead to death. Therefore, the development of efficient analytical methods …

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