Identification of fungal isolates by MALDI-TOF mass spectrometry in veterinary practice: validation of a web application.

Last updated on 29-10-2019 by Thibault Degiuli

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Peer reviewed scientific article

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Samenvatting:

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has emerged as a reliable method to identify fungal isolates. The success of this approach relies on the availability of exhaustive databases, but the latter were built with a focus on human pathogens. We assessed a large in-house database of reference spectra and a dedicated web application for their suitability for use in veterinary laboratories. A panel of 290 mold and yeast isolates representing 69 different fungal species was isolated from various animals (including pets, cattle, and zoo animals…

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