Rabies antibody response after two intradermal pre-exposure prophylaxis immunizations: An observational cohort study.

Last updated on 23-8-2019 by Anonymous (niet gecontroleerd)

Peer reviewed scientific article





BACKGROUND: Rabies is a lethal, but vaccine preventable disease. Vaccination uptake is however hampered by the time-consuming three-dose, 2½8-day schedule. The aim of this study was to examine whether adequate rabies antibody titers are reached after two intradermal (ID) doses of rabies vaccine, with a seven-day window. METHOD: We conducted an observational cohort study with military personnel. A titer was assessed by RFFIT, on the day of the third vaccination, to ensure an adequate rabies antibody response after ID immunization. RESULTS: After this abbreviated two-dose, seven-day I…

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