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Zoekresultaten - 42 results
The OPTIMUS International Consensus Guidance for Monitoring User-Reported Outcomes of Opioid Maintenance Treatment: a Delphi Study
Monitoring Opioid Agonist Maintenance Therapy (OMT) Overdose People who use drugs (PWUD) People who use opioids (PWUO) public health Substance use Treatment outcomes Abstract: Opioid use disorder is a major ...
Incorporating Patient-Reported Outcome Measures and Patient-Reported Experience Measures in Addiction Treatment Services in Belgium: Naturalistic, Longitudinal, Multicenter Cohort Study.
polysubstance use, while outpatients had fewer previous SUD treatments but received relatively more often opioid agonist treatment. Inpatients reported more attention-deficit/hyperactivity disorder symptoms and ...
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
chemical and biological techniques was used, to better reflect the risks to health and the environment. The samples investigated induced significant in vitro aryl hydrocarbon receptor (AhR) agonistic ...
Optimization of Long-Acting Bronchodilator Dose Ratios Using Isolated Guinea Pig Tracheal Rings for Synergistic Combination Therapy in Asthma and COPD.
Volume 15, Issue 8 (2022) Abstract: The co-administration of a long-acting β2-agonist (LABA), and a long-acting muscarinic antagonist (LAMA), has been shown to be beneficial in the management of ...
Insights From Early Clinical Trials Assessing Response to mRNA SARS-CoV-2 Vaccination in Immunocompromised Patients.
antimetabolites, CTLA4 agonists or JAK inhibitors, and vaccination with BNT162 b2 versus mRNA1273 vaccine. Finally, we review the first data on third dose mRNA vaccine administration in immunocompromised patients ...
Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation through a TLR2/MyD88 Pathway.
a nonpathogenic mold. A lack of TLR2 signaling recapitulated the exacerbation of the Th2 response observed in the absence of MyD88 signaling, whereas TLR2 agonist dampened the response induced with and conidia. ...
Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays
agonistic and antagonistic endocrine activity of 9 environmentally relevant PAH s using three different CALUX bioassays: The AhR- CALUX, The ER α- CALUX and PPAR γ- CALUX. For the PPAR γ- CALUX anthracene, ...
Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays
pyrene and fluorene showed a weak agonistic activity for the PPAR y receptor. Only BaP showed a weak antagonistic activity. In both the agonistic and antagonistic tests, no effects were observed in ...
PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.
nature of the calcium signals and the response regulation upon repeated exposures of astrocytes to the agonist (S)-3,5-dihydroxyphenylglycine. We show that upon repeated mGluR5 activations, a robust ...
Modulation de l’activité transcriptionelle de récepteurs nucléaires par les produits de migration de matériaux en plastique destinés aux jeunes enfants
activité sur aucun des récepteurs. La plupart des activités agonistes et antagonistes ont été observées respectivement sur le récepteur ER (29 substances sur 35) et PPAR y (20 substances sur 35). Aucune ...