Zoekresultaten - 9 results

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

disease development after infection with the virulent rabies virus strain CVS-11. Morbidity and mortality were significantly delayed in compared to mice, which was associated with a lower viral load, ...

Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

mycobacteria is characterised by glycolipids composed of different classes of mycolic acids (MA s; alpha-, keto-, and methoxy-) and sugars (trehalose, glucose, and arabinose). Studies using mutant Mtb strains ...

Urease activity represents an alternative pathway for Mycobacterium tuberculosis nitrogen metabolism31064

Mtb in macrophage as evidenced by comparable growth profiles for the mutant, wild type (WT) and complemented strains. In contrast, the urease-deficient mutant exhibited impaired in vitro growth compared ...

Biochemical and immunological characterization of a cpn60.1 knockout mutant of Mycobacterium bovis BCG1265

colonies on solid 7H11 medium than the parental and complemented strains. When growing on Sauton medium, the cpn60.1 mutant exhibits a thinner surface pellicle and is associated with higher culture filtrate ...

A limited role for SsrA/B in persistent Salmonella Typhimurium infections in pigs36796

mutant strain displayed decreased Salmonella Pathogenicity Island 2 (SPI-2) expression levels, showed a replication defect in mouse macrophages and was attenuated in a mouse model after oral inoculation. ...

A live Salmonella enterica serovar Enteritidis vaccine allows serological differentiation between vaccinated and infected animals36901

double mutant. All three mutants were less invasive than the wild-type strain in primary chicken cecal epithelial cells and the human epithelial cell line T84 and less efficiently internalized in the ...

Induction of cytotoxic T-cell responses against culture filtrate antigens in Mycobacterium bovis bacillus Calmette-Guérin-infected mice.

macrophages. Using the MHC class I mutant B6.C-H-2bm13 mouse strain, we demonstrate that cytotoxic T lymphocytes (CTL s) recognize CFA gs exclusively in association with D(b) molecules. These Ags are ...

Mapping of TH1 helper T-cell epitopes on major secreted mycobacterial antigen 85A in mice infected with live Mycobacterium bovis BCG36652

histocompatibility complex class II mutant B6.C.bm12 mice, carrying a mutant I-A beta bm12 allele on an H-2b background, reacted only very weakly to the 85A peptides. Reactive T cells isolated from lungs of ...

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