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Zoekresultaten - 122 results
Sphaeropsidin A C15-C16 Cross-Metathesis Analogues with Potent Anticancer Activity.
A L; Mathieu, Véronique; Kornienko, Alexander Source: ChemMedChem, Volume 19, Issue 18 (2024) Keywords: Antineoplastic Agents Ascomycota Cell Line, Tumor Cell Proliferation Dose-Response Relationship, ...
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
Elskens, Marc Source: Environ Sci Pollut Res Int, Volume 31, Issue 43 (2024) Keywords: Animals Basic Helix-Loop-Helix Transcription Factors Belgium Cell Line Embryo, Nonmammalian Growth Inhibitors ...
Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals.
* Source: Chem Res Toxicol, Volume 37, Issue 3 (2024) Keywords: Animals Biomarkers Cell Line DNA Damage Gene Expression Profiling Humans Transcriptome Abstract: To modernize genotoxicity assessment and reduce ...
NextGEM: Next-Generation Integrated Sensing and Analytical System for Monitoring and Assessing Radiofrequency Electromagnetic Field Exposure and Health.
Colussi, Loek; Pruppers, Mathieu; Baaken, Dan; Bogdanova, Anna Source: Int J Environ Res Public Health, Volume 20, Issue 12 (2023) Keywords: Cell Phone Electromagnetic Fields environmental exposure Humans ...
Effects of long-term exposure to 50 Hz magnetic fields on cell viability, genetic damage, and sensitivity to mutagen-induced damage.
damage induced by known mutagens) were investigated in the human B lymphoblastoid (TK6) cell line. Cells were exposed to 50 Hz MF at three selected magnetic flux densities (i.e., 10, 100, and 500 μT) for ...
In vitro and in vivo local tolerability of a synergistic anti-tuberculosis drug combination intended for pulmonary delivery.
and monocytes were exposed to concentrations around and above their minimal inhibitory concentration (MIC). The VAN had no inhibitory activity on the tested human cell lines, even at a concentration 125 ...
Impact of experimental design factors on the potency of genotoxicants in in vitro test
that of more traditional statistical methods based on lowest observed genotoxic effect levels. When comparing the in vitro MN results obtained in both cell lines with the BMD covariate approach, ...
Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo
composed of small or large agglomerates with similar dispersion medium composition. For in vitro testing, human bronchial epithelial (HBE), colon epithelial (Caco2) and monocytic (THP-1) cell lines were ...
Is aggregated synthetic amorphous silica toxicologically relevant?
stronger effects in all the cell lines than the aggregated suspension (AGGR). We then compared DE- AGGR with 2 suspensions fractionated from AGGR: the precipitated fraction (PREC) and the supernatant ...
NGS for (Hemato-) Oncology in Belgium: Evaluation of Laboratory Performance and Feasibility of a National External Quality Assessment Program
in Belgium. DNA samples derived from cell line mixes and artificially mutated cell lines, designed to carry variants of clinical relevance occurring in solid tumors, hematological malignancies, and ...