Zoekresultaten - 6 results

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

tool can improve human safety assessment of chemicals in general by basing predictions on mechanistic toxicogenomics information. Health Topics:  Health and environment Santé et environnement Gezondheid ...

Scientific opinion on the risk for public and animal health related to the presence of sterigmatocystin in food and feed

Dietary exposure Dna effect effects European European Commission exposure exposure assessment fat feed food Food Chain Food Safety health Human human health IS Kidney Less Limit of Detection Liver Lung ...

Scientific Opinion of the EFSA Panel on Plant Protection Products and their Residues (PPR) on Guidance on dermal absorption

(2012) Keywords: Animal Animals approach approaches assessment data dermal absorption Design EU EVALUATION guidance guidance document Human IS ON plant plant protection product PRODUCTS rats recommendation ...

Biosafety aspects of modified vaccinia virus Ankara (MVA)-based vectors used for gene therapy or vaccination.

the assessment of potential risks for human health and the environment. The purpose of the present paper is to highlight some biological characteristics of MVA and MVA-based recombinant vectors and to ...

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