Zoekresultaten - 4 results

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria. 34 clinical M. tuberculosis isolates were investigated for their resistance profile to four different drugs (rifampicin, isoniazid, ethambutol and linezolid), yielding a 100% concordance to the ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

using the approach called RNA tag-Seq, multiple samples were combined in one run, reducing time and cost.   Material/methods: For each drug (isoniazid, rifampicin, ethambutol, capreomycin, amikacin, ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

multiple samples were combined in one run, reducing time and cost.   Material/methods: For each drug (isoniazid, rifampicin, ethambutol, capreomycin, amikacin, linezolid, moxifloxacin and bedaquilin), twice ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

of RNA biomarkers for ten 1st-line, 2nd-line and new drugs. Taking isoniazid as proof of principle, we present a biomarker set of 5 responsive genes and 3 normalizing genes, which enables to ...

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