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In Vivo Kinetics and Biotransformation of Aflatoxin B1 in Dairy Cows Based on the Establishment of a Reliable UHPLC-MS/MS MethodDataSheet1.docx
Chemistry, Volume 9 (2021) Keywords: Aflatoxins biotransformation dairy cow in vivo kinetics UHPLC-MS/MS Abstract: The in vivo kinetics of aflatoxin B1 (AFB1) and its carry-over as aflatoxin M1 (AFM1) in ...
Comprehensive toxicokinetic analysis reveals major interspecies differences in absorption, distribution and elimination of citrinin in pigs and broiler chickens
L/kg after IV administration). However, plasma protein binding did not differ statistically significant (91-98%). It is imperative to further investigate biotransformation and elimination pathways in ...
Insights into In Vivo Absolute Oral Bioavailability, Biotransformation, and Toxicokinetics of Zearalenone, α-Zearalenol, β-Zearalenol, Zearalenone-14-glucoside, and Zearalenone-14-sulfate in Pigs
Publication Type: Peer reviewed scientific article Authors: Amelie Catteuw; Nathan Broekaert; Siegrid De Baere; Marianne Lauwers; Elke Gasthuys; Bart Huybrechts; A. Callebaut; Lada Ivanova; Silvio Uhlig; Marthe De Boevre; S. De Saeger; Ronette Gehring; De ...
Cytome assay in two cell lines exposed to ELF-magnetic fields: An investigation on the relation between exposure to ELF-magnetic fields and an alleged increased risk for Alzheimer's disease.
enzyme systems that allow metabolisation (biotransformation) of chemicals the way this happens in the living organism. SH- SY5Y cells are human neuroblastoma cells. This means that they are more relevant ...
CYP3A5 and ABCB1 polymorphisms influence tacrolimus concentrations in peripheral blood mononuclear cells after renal transplantation.
prospective study investigated the effect of genetic polymorphisms in a biotransformation enzyme (CYP3A5) and a transporter protein (ABCB1) on tacrolimus (Tac) whole blood concentrations in renal ...
1199G> A and 2677G> T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation.
polymorphisms in biotransformation enzymes or transporter proteins, such as CYP3A5 and P-glycoprotein (ABCB1), in donors and/or recipients, appear as important determinants of the Tac blood pharmacokinetics. ...