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Zoekresultaten - 15 results
Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.
environmental risk assessment oncolytic virus shedding Abstract: Attenuated and/or genetically modified oncolytic viruses (OV) gain increasing interest as a promising approach for cancer therapy. Beside the ...
Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
Keersmaecker Source: Int J Mol Sci, Volume 21, Issue 15 (2020) Keywords: Betacoronavirus Coronavirus Infections Databases, Genetic Genome, Viral Humans Open Reading Frames Pandemics Pneumonia, Viral ...
Lineages Within the Trichophyton rubrum Complex.
approach, using molecular phylogenetic techniques, MALDI- TOF mass spectrometry and physiological and morphological analysis, we re-evaluated the T. rubrum complex. Our results support four genetic lineages ...
Genome Editing in Agriculture: Methods, Applications, and Governance—A paper in the series on The Need for Agricultural Innovation to Sustainably Feed the World by 2050
issue paper describes how genome editing is performed, the types of “edits” that can be made, how the process relates to traditional breeding and conventional genetic engineering, and the potential ...
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Abstract: Prior to the downstream development of chemical substances, including pharmaceuticals and cosmetics, their influence on the genetic apparatus has to be tested. Several in vitro and in vivo assays ...
Biosafety considerations for attenuated measles virus vectors used in virotherapy and vaccination.
(2016) Keywords: Animals Containment of Biohazards Genetic Vectors Humans Measles Measles Vaccine Measles virus Membrane Cofactor Protein mice Oncolytic Virotherapy Vaccination Vaccines, Attenuated Virus ...
Investigations of plant-derived products with the in vitro comet assay
Publication Type: Peer reviewed scientific article Authors: Luc Verschaeve Source: Frontiers in Genetics, Volume 6 (2015) Keywords: Comet Assay medicinal plants SCREENING Vitotox test Health ...
Development of giant bacteriophage phiKZ is independent of the host transcription apparatus
RNA Polymerases electronic Enzymes enzymology Functional gene Gene Expression Regulation,Viral Genes Genetic genetics Genome Genome,Viral growth & development Host-Pathogen Interactions im INFECTION ...
Environmental risk assessment of clinical trials involving modified vaccinia virus Ankara (MVA)-based vectors.
Animals Clinical Trials as Topic Genetic Therapy Genetic Vectors Hazardous Substances Humans Risk Assessment Vaccination vaccinia virus Viral Vaccines Abstract: The modified vaccinia virus Ankara (MVA) ...
Testing chemical agents with the cytokinesis-block micronucleus cytome assay.
proved to be a suitable tool to investigate genetic effects of environmental agents and to provide insight into their working mechanisms as all chemicals tested showed the expected response. Health ...