Zoekresultaten - 387 results
Constitutive downregulation protein kinase C epsilon in hSOD1 astrocytes influences mGluR5 signaling and the regulation of glutamate uptake.
neuron degeneration in amyotrophic lateral sclerosis (ALS) is a non-cell-autonomous process and that impaired glutamate clearance by astrocytes, leading to excitotoxicity, could participate in progression ...
Helminth-induced IL-4 expands bystander memory CD8 T cells for early control of viral infection.
with parasitic helminths can imprint the immune system to modulate bystander inflammatory processes. Bystander or virtual memory CD8 T cells (T) are non-conventional T cells displaying memory properties ...
Batch release of vaccines in Europe: from method transfer to first commercial batch available on the market. Straightforward approach that requires a proactive mindset of the manufacturer.
OCABR is valid for all other Member States, which is also known as mutual recognition. Although the process of batch release in Europe is straightforward and clearly laid down in directives, it is ...
Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid
from the same class. Although delamanid is found to inhibit cell wall synthesis, the expression of genes involved in this process were only mildly affected. In contrast, a clear parallel was found with ...
Integrated Care Models for Managing and Preventing Frailty: A Systematic Review for the European Joint Action on Frailty Prevention (ADVANTAGE JA).
diseases, processes or interventions and service models that did not report data, 42 full papers met the inclusion criteria. The evidence showed that few models of integrated care were specifically designed ...
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set.
variation affects cellular processes. These effects may manifest as distinct phenotypic differences between individuals or result in the development of disease. Physical interactions between molecules are the ...
The eukaryotic linear motif resource- 2018 update.
Viruses Abstract: Short linear motifs (SL iMs) are protein binding modules that play major roles in almost all cellular processes. SL iMs are short, often highly degenerate, difficult to characterize and ...
Exploring Short Linear Motifs Using the ELM Database and Tools.
prediction of short linear motifs (SL iMs). SL iMs are compact, degenerate peptide segments found in many proteins and essential to almost all cellular processes. However, despite their abundance, SL iMs ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.
anti-tuberculous drug from the same class. Although delamanid is found to inhibit cell wall synthesis, the expression of genes involved in this process were only mildly affected. In contrast, a clear parallel was ...
Feasibility study on drug consumption rooms in Belgium
the implementation process; and monitoring and evaluation. Health Topics: Quality of healthcare Qualité des soins de santé Kwaliteit van de gezondheidszorg Manuscript versions: File: Version: ...