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Zoekresultaten - 6 results
Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
identified following screening against the most relevant trypanosome species. Selected hit compounds were extensively tested for metabolic stability, potency in mouse models for the various species, ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
Investigations of plant-derived products with the in vitro comet assay
Publication Type: Peer reviewed scientific article Authors: Luc Verschaeve Source: Frontiers in Genetics, Volume 6 (2015) Keywords: Comet Assay medicinal plants SCREENING Vitotox test Health ...
Revealing the identification power of CCS: A novel approach applied to pesticide analysis in food
analysis,LC-IMS-HRMS,identity confirmation, ON performance pesticide Pesticides Residue result results Sample Samples SCREENING Screening method separation series Solutions Strategies Strategy System Test time use values ...
Scientific Opinion of the EFSA Panel on Plant Protection Products and their Residues (PPR) on Evaluation of the toxicological relevance of pesticide metabolites for dietary risk assessment
ActivityRelationship,(Q)SAR,read-across,stereoisomer,Threshold of Toxicological Concern (TTC) Pesticides plant plant protection product PRODUCTS Ratio Residue result results risk Risk Assessment SAFETY SCREENING study threshold use VALIDATION Validation study ...
Mutagenicity, antimutagenicity and cytotoxicity evaluation of South African Podocarpus species
South Africa. In vitro pharmacological screening of leaf and stem extracts of these species exhibited potent antimicrobial, anti-inflammatory, anti-tyrosinase, anthelmintic, acetylcholinesterase ...