Zoekresultaten - 5 results

Urinary nicotine metabolites: usefulness as biomarkers of smoking status

and further to trans-3’-hydroxycotinine (HCOT) by the cytochrome P450 CYP2A6 enzyme. It has been demonstrated that the ratio of HCOT to COT is an index of CYP2A6 activity, thus a marker of nicotine ...

Scientific Opinion of the EFSA Panel on Plant Protection Products and their Residues (PPR) on Evaluation of the toxicological relevance of pesticide metabolites for dietary risk assessment

ActivityRelationship,(Q)SAR,read-across,stereoisomer,Threshold of Toxicological Concern (TTC) Pesticides plant plant protection product PRODUCTS Ratio Residue result results risk Risk Assessment SAFETY SCREENING study threshold use VALIDATION Validation study ...

Thyroid cancer incidence near nuclear sites in Belgium: An ecological study at small geographical level.

excess incidence of thyroid cancer among people living in the vicinity of the four nuclear sites at the smallest Belgian geographical level. Rate ratios were obtained from a Bayesian hierarchical model for ...

Childhood leukemia near nuclear sites in Belgium: An ecological study at small geographical level.

statistical sector level. RESULTS: Higher incidence rate ratios were found for children <15 years (7 cases, RR = 3.01, 95% CI: 1.43;6.35) and children <5 years (< 5 cases, RR = 3.62, 95% CI: 1.35;9.74) ...

In utero exposure to parabens and early childhood BMI z-scores- Associations between placental ethyl paraben, longitudinal BMI trajectories and cord blood metabolic biomarkers.

and 0.35 ng/g respectively, with only EtP showing sufficient (88%) measurements above LOD for further analyses. An interquartile ratio (IQR) increase in placental EtP was associated with an increase of ...

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