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Zoekresultaten - 9 results

Pyrogen testing of phage therapeutic products

these last years, with treatments provided to more than 100 patients, against more than 10 different bacterial species. Therapeutic phage products are produced  in a bacterial host strain, hence pyrogen ...

Homologous versus heterologous prime-boost COVID-19 vaccination: impact on clinical severity of Omicron among hospitalized COVID-19 patients in Belgium

SARS-CoV-2 Omicron infection among hospitalized patients in Belgium, and if this effect is homogenous across different Omicron sub-lineages. Methods Observational data from existing national surveillance ...

The GEONs API-fingerprint program: Tackling falsifications of APIs

Official Medicines Control Laboratory (OMCL) Network (GEON) different initiatives were taken to augment the analysis and market surveillance of API s used by the different manufacturers. Despite the efforts, ...

Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium

spectrometry (UHPLC- MS2) screening method is presented, taking only 15 minutes, for the identification of 36 different antimicrobials and 1 beta-lactamase inhibitor. Furthermore, upon identification, ...

Identification of Flavouring Substances of Genotoxic Concern Present in E-Cigarette Refills

genotoxic substances in e-liquid flavours. 77 e-liquids, representative for the different flavour categories, were collected on the Belgian market and screened for their chemical composition using GC- MS. By ...

First Belgian national EQA for special stains in histopathology

82%, for the HE stain97%, for the PAS stain 82%, for the reticulin stain 76%, for the trichrome stain 72% and for the Perls stain92%. A statistically significant difference between results obtained with ...

Classification trees based on infrared spectroscopic data to discriminate between genuine and counterfeit medicines

Chemometrics Society, NA (2012) Keywords: ALL an AS chemistry Class classification Common Counterfeit Drugs Countries data developing differences discrimination DRUG drugs external health Internet IS Literature ...

Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production

minimize time loss, the amount of TeNT is often monitored during and at the end of the bacterial culturing. The different methods that are currently available to assess the amount of TeNT in the bacterial ...

Non-sterile pharmaceutical water: source of life and/or potential carrier for opportunistic pathogens

synthesis, during production of the finished product or as a cleaning agent for rinsing vessels, equipment, primary packaging materials, etc. Depending on the pharmaceutical application, different grades of ...

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